5CQ3
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 6-Hydroxypicolinic acid (SGC - Diamond I04-1 fragment screening)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 120 | 14057.1 | 1 | UniProt (Q9UIF8) Pfam (PF00439) In PDB | Homo sapiens (Human) | hWALp4 |
| 2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | A | 6-hydroxypyridine-2-carboxylic acid | non-polymer | 139.1 | 1 | Chemie (53B) | |||
| 4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1972 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Tyr 1853 | - | expression tag |
| Phe 1854 | - | expression tag |
| Gln 1855 | - | expression tag |
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14057.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 436.3 | |
| All* | Total formula weight | 14493.5 |
