5CNJ

mGlur2 with glutamate analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metabotropic glutamate receptor 2	polymer	503	55670.8	2	UniProt (Q14416) Pfam (PF01094)	Homo sapiens (Human)	mGluR2
2	C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	D, E (A, B)	(1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid	non-polymer		284.3	2	Chemie (52Q)
4	F, G (A, B)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, B: 2 - 493 (UniProt: Q14416)

PDB	External Database	Details
Met -1	-	expression tag
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 234	Cys 234	conflict
Glu 494	-	expression tag
Gly 495	-	expression tag
His 496	-	expression tag
His 497	-	expression tag
His 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	111341.6
Non-Polymers*	Number of molecules	3
	Total formula weight	789.8
All*	Total formula weight	112131.4

*Water molecules are not included.