5CNI

mGlu2 with Glutamate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Metabotropic glutamate receptor 2	polymer	503	55712.8	2	UniProt (Q14416) Pfam (PF01094) In PDB	Homo sapiens (Human)	mGluR2
2	A, B	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
3	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
6		water	water		18.0	239	Chemie (HOH)

Sequence modifications

A, B: 2 - 493 (UniProt: Q14416)

PDB	External Database	Details
Met -1	-	expression tag
Ala 0	-	expression tag
Leu 1	-	expression tag
Ser 234	Cys 234	conflict
Glu 302	Ser 302	conflict
Glu 494	-	expression tag
Gly 495	-	expression tag
His 496	-	expression tag
His 497	-	expression tag
His 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	111425.7
Non-Polymers*	Number of molecules	10
	Total formula weight	1296.0
All*	Total formula weight	112721.6

*Water molecules are not included.