5CMM
Crystal structure of the GluK2EM LBD dimer assembly complex with 2S,4R-4-methylglutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor ionotropic, kainate 2 | polymer | 259 | 29356.6 | 1 | UniProt (P42260) UniProt (Q13002) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluK2,Glutamate receptor 6,GluR6,Excitatory amino acid receptor 4,EAA4 |
| 2 | B (A) | 2S,4R-4-METHYLGLUTAMATE | non-polymer | 160.1 | 1 | Chemie (SYM) | |||
| 3 | C (A) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence modifications
A: 2 - 117 (UniProt: P42260)
A: 120 - 259 (UniProt: Q13002)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Thr 91 | Ala 518 | engineered mutation |
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 142 | Ala 689 | engineered mutation |
| Ser 174 | Asn 721 | engineered mutation |
| Leu 188 | Phe 735 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29356.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 160.1 | |
| All* | Total formula weight | 29516.8 |
