5CKV

DAHP synthase from Mycobacterium tuberculosis, fully inhibited by tyrosine, phenylalanine, and tryptophan

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phospho-2-dehydro-3-deoxyheptonate aldolase AroG	polymer	472	51891.5	2	UniProt (O53512) Pfam (PF01474)	Mycobacterium tuberculosis	3-deoxy-D-arabino-heptulosonate 7-phosphate synthase,DAHP synthase,Phospho-2-keto-3-deoxyheptonate aldolase
2	C, L (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
3	D, E, F, N, O (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	G, H, P, Q, R (A, B)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
5	I, T (A, B)	TRYPTOPHAN	non-polymer		204.2	2	Chemie (TRP)
6	J, M (A, B)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
7	K, U (A, B)	PHENYLALANINE	non-polymer		165.2	2	Chemie (PHE)
8	S (B)	TYROSINE	non-polymer		181.2	1	Chemie (TYR)
9	V, W (A, B)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

A, B: 1 - 462 (UniProt: O53512)

PDB	External Database	Details
Met -9	-	initiating methionine
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103783.1
Non-Polymers*	Number of molecules	19
	Total formula weight	2041.6
All*	Total formula weight	105824.7

*Water molecules are not included.