5CJP
The Structural Basis for Cdc42-Induced Dimerization of IQGAPs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a | polymer | 179 | 19758.7 | 4 | UniProt (A0A024RAE4) Pfam (PF00071) UniProt (by SIFTS) (P60953) | Homo sapiens (Human) | |
| 2 | E, F (E, F) | Ras GTPase-activating-like protein IQGAP2 | polymer | 387 | 44058.1 | 2 | UniProt (Q13576) Pfam (PF00616) | Homo sapiens (Human) | |
| 3 | G, I, K, M (A, B, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) | |||
| 4 | H, J, L, N (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 177 (UniProt: A0A024RAE4)
E, F: 875 - 1258 (UniProt: Q13576)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Leu 61 | Gln 61 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 872 | - | expression tag |
| Ala 873 | - | expression tag |
| Met 874 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 167151.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2189.9 | |
| All* | Total formula weight | 169341.1 |
