5CJ6
Crystal Structure of a Selective Androgen Receptor Modulator Bound to the Ligand Binding Domain of the Human Androgen Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 283 | 32688.8 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (B) | small peptide | polymer | 10 | 1110.2 | 1 | UniProt (by SIFTS) (P10275) | synthetic construct | |
| 3 | C (A) | 2-chloro-4-{[(1R,2R)-2-hydroxy-2-methylcyclopentyl]amino}-3-methylbenzonitrile | non-polymer | 264.8 | 1 | Chemie (51Y) | |||
| 4 | D (A) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A: 641 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Ser 639 | - | expression tag |
| Leu 640 | - | expression tag |
| Glu 920 | - | expression tag |
| Gly 921 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33799.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 264.8 | |
| All* | Total formula weight | 34063.8 |
