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5CFQ

Crystal structure of anemone STING (Nematostella vectensis) in complex with 2',3' cGAMP, c[G(2',5')pA(3',5')p]

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Stimulator of Interferon Genespolymer18721725.72UniProt (A7SLZ2)
Pfam (PF15009)
Nematostella vectensis (Starlet sea anemone)Predicted protein
2C, E
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
3D
(B)
cGAMPnon-polymer674.41Chemie (1SY)
4F, G
(A, B)
waterwater18.056Chemie (HOH)
Sequence modifications
A, B: 193 - 377 (UniProt: A7SLZ2)
PDBExternal DatabaseDetails
Gly 191-expression tag
Ser 192-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43451.4
Non-Polymers*Number of molecules3
Total formula weight866.5
All*Total formula weight44318.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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