5CFP
Crystal structure of anemone STING (Nematostella vectensis) 'humanized' F276K in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]'
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Stimulator of Interferon Genes | polymer | 202 | 23467.7 | 2 | UniProt (A7SLZ2) Pfam (PF15009) In PDB | Nematostella vectensis (Starlet sea anemone) | Predicted protein |
| 2 | A, B | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) | non-polymer | 690.4 | 2 | Chemie (C2E) | |||
| 3 | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A, B: 178 - 377 (UniProt: A7SLZ2)
| PDB | External Database | Details |
|---|---|---|
| Gly 176 | - | expression tag |
| Ser 177 | - | expression tag |
| Lys 276 | Phe 276 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46935.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1380.8 | |
| All* | Total formula weight | 48316.2 |
