5CCC

wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Dihydrofolate reductase	polymer	159	18019.3	1	UniProt (P0ABQ5) Pfam (PF00186) UniProt (by SIFTS) (P0ABQ4) In PDB	Escherichia coli
2	A	5,10-DIDEAZATETRAHYDROFOLIC ACID	non-polymer		443.5	1	Chemie (DDF)
3	A	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP)
4		water	water		18.0	134	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18019.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1186.9
All*	Total formula weight	19206.2

*Water molecules are not included.