5CBL
Crystal structure of the C-terminal domain of human galectin-4 with lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, C, D) | Galectin-4 | polymer | 148 | 16375.6 | 3 | UniProt (P56470) Pfam (PF00337) | Homo sapiens (human) | Gal-4,Antigen NY-CO-27,L-36 lactose-binding protein,L36LBP,Lactose-binding lectin 4 |
| 2 | B (B) | Galectin-4 | polymer | 148 | 16451.7 | 1 | UniProt (P56470) Pfam (PF00337) | Homo sapiens (human) | Gal-4,Antigen NY-CO-27,L-36 lactose-binding protein,L36LBP,Lactose-binding lectin 4 |
| 3 | E, F, G, H (E, F, G, H) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 4 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 4 | I (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | J, K (B, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A, C, D: 179 - 323 (UniProt: P56470)
B: 179 - 323 (UniProt: P56470)
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Glu 177 | - | expression tag |
| Phe 178 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Glu 177 | - | expression tag |
| Phe 178 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65578.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1369.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 280.3 | |
| All* | Total formula weight | 67228.0 |
