5CBL
Crystal structure of the C-terminal domain of human galectin-4 with lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Galectin-4 | polymer | 148 | 16375.6 | 4 | UniProt (P56470) Pfam (PF00337) In PDB | Homo sapiens (Human) | Gal-4,Antigen NY-CO-27,L-36 lactose-binding protein,L36LBP,Lactose-binding lectin 4 |
| 2 | E, F, G, H | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 4 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 3 | B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 4 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | B, C | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 179 - 323 (UniProt: P56470)
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Glu 177 | - | expression tag |
| Phe 178 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65502.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1369.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 358.4 | |
| All* | Total formula weight | 67230.1 |
