5C8S
Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligands SAH and GpppA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Non-structural protein 10 | polymer | 144 | 15268.4 | 2 | UniProt (P0C6X7) Pfam (PF09401) | Human SARS coronavirus (SARS-CoV) | nsp10 |
| 2 | B, D (B, D) | Guanine-N7 methyltransferase | polymer | 527 | 59967.4 | 2 | UniProt (P0C6X7) Pfam (PF06471) | Human SARS coronavirus (SARS-CoV) | nsp14 |
| 3 | E, F, G, H, I... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 4 | J, R (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | K, S (B, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 6 | L, T (B, D) | GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 772.4 | 2 | Chemie (G3A) |
Sequence modifications
A, C: 1 - 139 (UniProt: P0C6X7)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150471.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3016.3 | |
| All* | Total formula weight | 153488.0 |
