5C8S

Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligands SAH and GpppA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Non-structural protein 10	polymer	144	15268.4	2	UniProt (P0C6X7) Pfam (PF09401) In PDB	Human SARS coronavirus (SARS-CoV)	nsp10
2	B, D	Guanine-N7 methyltransferase	polymer	527	59967.4	2	UniProt (P0C6X7) Pfam (PF06471) In PDB	Human SARS coronavirus (SARS-CoV)	nsp14
3	A, B, C, D	ZINC ION	non-polymer		65.4	10	Chemie (ZN)
4	B, D	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	B, D	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
6	B, D	GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE	non-polymer		772.4	2	Chemie (G3A)

Sequence modifications

A, C: 1 - 139 (UniProt: P0C6X7)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	150471.7
Non-Polymers*	Number of molecules	16
	Total formula weight	3016.3
All*	Total formula weight	153488.0

*Water molecules are not included.