5C8S
Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligands SAH and GpppA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Non-structural protein 10 | polymer | 144 | 15268.4 | 2 | UniProt (P0C6X7) Pfam (PF09401) | Human SARS coronavirus (SARS-CoV) | nsp10 |
| 2 | B, D (B, D) | Guanine-N7 methyltransferase | polymer | 527 | 59967.4 | 2 | UniProt (P0C6X7) Pfam (PF06471) | Human SARS coronavirus (SARS-CoV) | nsp14 |
| 3 | E, F, G, H, I... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 4 | J, R (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | K, S (B, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 6 | L, T (B, D) | GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 772.4 | 2 | Chemie (G3A) PubChem (135450590) PubChem (162789443) PubChem (171037886) PubChem (136948342) |
Sequence modifications
A, C: 1 - 139 (UniProt: P0C6X7)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150471.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3016.3 | |
| All* | Total formula weight | 153488.0 |
