5C79

PH domain of ASAP1 in complex with diC4-PtdIns(4,5)P2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Arf-GAP	polymer	150	17253.2	2	UniProt (Q9QWY8) Pfam (PF00169)	Mus musculus (Mouse)	130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein,ADP-ribosylation factor-directed GTPase-activating protein 1,ARF GTPase-activating protein 1,Development and differentiation-enhancing factor 1,Differentiation-enhancing factor 1,PIP2-dependent ARF1 GAP
2	C, E, F (A, B)	(2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE	non-polymer		634.4	3	Chemie (PBU)
3	D (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	G, H (A, B)	water	water		18.0	222	Chemie (HOH)

Sequence modifications

A, B: 325 - 451 (UniProt: Q9QWY8)

PDB	External Database	Details
Met 302	-	expression tag
Gly 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
Ser 314	-	expression tag
Ser 315	-	expression tag
Gly 316	-	expression tag
His 317	-	expression tag
Ile 318	-	expression tag
Asp 319	-	expression tag
Asp 320	-	expression tag
Asp 321	-	expression tag
Lys 322	-	expression tag
His 323	-	expression tag
Met 324	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34506.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1938.5
All*	Total formula weight	36445.0

*Water molecules are not included.