5C3R

Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-hydroxymethyluracil (5hmU)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thymine dioxygenase	polymer	343	38538.2	4	UniProt (Q7RYZ9) Pfam (PF14226) Pfam (PF03171)	Neurospora crassa
2	E, N, S, X (A, B, C, D)	NICKEL (II) ION	non-polymer		58.7	4	Chemie (NI)
3	F, O, T, Y (A, B, C, D)	2-OXOGLUTARIC ACID	non-polymer		146.1	4	Chemie (AKG)
4	G, P, U, Z (A, B, C, D)	5-HYDROXYMETHYL URACIL	non-polymer		142.1	4	Chemie (HMU)
5	AA, BA, CA, H, I... (D, A, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	13	Chemie (EDO)
6	DA, EA, FA, GA (A, B, C, D)	water	water		18.0	557	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 333 (UniProt: Q7RYZ9)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Leu 334	-	expression tag
Glu 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154153.0
Non-Polymers*	Number of molecules	25
	Total formula weight	2194.5
All*	Total formula weight	156347.5

*Water molecules are not included.