5C3G

Crystal structure of Bcl-xl bound to BIM-MM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bcl-2-like protein 1,Bcl-2-like protein 1	polymer	153	17506.5	1	UniProt (Q64373) UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB	Mus musculus (House Mouse)	Bcl2-L-1,Apoptosis regulator Bcl-X, Bcl-xl,Bcl2-L-1,Apoptosis regulator Bcl-X,Bcl-xl
2	B	Bcl-2-like protein 11	polymer	22	2611.0	1	UniProt (O43521) Pfam (PF08945) In PDB	Homo sapiens	Bcl2-L-11,Bcl2-interacting mediator of cell death
3		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A: 1 - 26 (UniProt: Q64373)
A: 83 - 209 (UniProt: Q07817)
B: 88 - 108 (UniProt: O43521)

PDB	External Database	Details
Ace 87	-	acetylation
Nle 96	Arg 64	engineered mutation
Nle 100	Glu 68	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	20117.5
All*	Total formula weight	20117.5

*Water molecules are not included.