5C2J
Complex structure of the GAP domain of MgcRacGAP and Cdc42
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rac GTPase-activating protein 1 | polymer | 208 | 23192.9 | 1 | UniProt (Q9H0H5) Pfam (PF00620) | Homo sapiens (Human) | Male germ cell RacGap,MgcRacGAP,Protein CYK4 homolog,HsCYK-4 |
| 2 | B (B) | Cell division control protein 42 homolog | polymer | 198 | 21803.1 | 1 | UniProt (P60766) Pfam (PF00071) | Mus musculus (Mouse) | G25K GTP-binding protein |
| 3 | C (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E (B) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A: 346 - 546 (UniProt: Q9H0H5)
B: 1 - 191 (UniProt: P60766)
| PDB | External Database | Details |
|---|---|---|
| Gly 339 | - | expression tag |
| Ser 340 | - | expression tag |
| Ser 341 | - | expression tag |
| Gly 342 | - | expression tag |
| Ser 343 | - | expression tag |
| Ser 344 | - | expression tag |
| Gly 345 | - | expression tag |
| Ser 518 | Leu 518 | See Sequence details |
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44995.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 551.5 | |
| All* | Total formula weight | 45547.4 |
