5BZG
Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CD44 antigen | polymer | 151 | 16855.8 | 1 | UniProt (P15379) Pfam (PF00193) | Mus musculus (Mouse) | Extracellular matrix receptor III,ECMR-III,GP90 lymphocyte homing/adhesion receptor,HUTCH-I,Hermes antigen,Hyaluronate receptor,Lymphocyte antigen 24,Ly-24,Phagocytic glycoprotein 1,PGP-1,Phagocytic glycoprotein I,PGP-I |
| 2 | B (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | C (A) | 2-methyl-1,2,3,4-tetrahydroisoquinolin-5-amine | non-polymer | 162.2 | 1 | Chemie (4X6) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A: 23 - 173 (UniProt: P15379)
| PDB | External Database | Details |
|---|---|---|
| Met 23 | His 21 | engineered mutation |
| Asn 24 | Gln 22 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16855.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 336.4 | |
| All* | Total formula weight | 17192.2 |
