5BZE
Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CD44 antigen | polymer | 151 | 16855.8 | 1 | UniProt (P15379) Pfam (PF00193) In PDB | Mus musculus (Mouse) | Extracellular matrix receptor III,ECMR-III,GP90 lymphocyte homing/adhesion receptor,HUTCH-I,Hermes antigen,Hyaluronate receptor,Lymphocyte antigen 24,Ly-24,Phagocytic glycoprotein 1,PGP-1,Phagocytic glycoprotein I,PGP-I |
| 2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | [(1S)-1,2,3,4-tetrahydroisoquinolin-1-yl]methanol | non-polymer | 163.2 | 1 | Chemie (68N) | |||
| 5 | A | [(1R)-1,2,3,4-tetrahydroisoquinolin-1-yl]methanol | non-polymer | 163.2 | 1 | Chemie (6BT) | |||
| 6 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 25 - 173 (UniProt: P15379)
| PDB | External Database | Details |
|---|---|---|
| Met 23 | - | initiating methionine |
| Asn 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16855.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 500.6 | |
| All* | Total formula weight | 17356.4 |
