5BZC
Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CD44 antigen | polymer | 151 | 16839.7 | 1 | UniProt (P15379) Pfam (PF00193) In PDB | Mus musculus (Mouse) | Extracellular matrix receptor III,ECMR-III,GP90 lymphocyte homing/adhesion receptor,HUTCH-I,Hermes antigen,Hyaluronate receptor,Lymphocyte antigen 24,Ly-24,Phagocytic glycoprotein 1,PGP-1,Phagocytic glycoprotein I,PGP-I |
2 | A | 4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline | non-polymer | 161.2 | 1 | Chemie (4WT) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A: 24 - 173 (UniProt: P15379)
PDB | External Database | Details |
---|---|---|
Asn 24 | Gln 22 | engineered mutation |
Asp 174 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16839.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 239.4 | |
All* | Total formula weight | 17079.1 |