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5BYZ

ERK5 in complex with small molecule

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 7polymer34839826.91UniProt (Q13164)
Pfam (PF00069)
Homo sapiens (Human)MAPK 7,Big MAP kinase 1,BMK-1,Extracellular signal-regulated kinase 5,ERK-5
2B
(A)
4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamidenon-polymer465.61Chemie (4WE)
3C, D, E, F, G...
(A)
GLYCEROLnon-polymer92.16Chemie (GOL)
4I
(A)
waterwater18.0336Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39826.9
Non-Polymers*Number of molecules7
Total formula weight1018.1
All*Total formula weight40845.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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