5BYG

X-ray structure of AAV2 OBD-AAVS1 complex 2:1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Protein Rep78	polymer	213	24551.8	4	UniProt (Q89268) Pfam (PF08724)	Adeno-associated virus 2 (AAV-2)
2	E, G (E, G)	DNA (5'-D(*CP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*T)-3')	polymer	21	6343.1	2		Homo sapiens
3	F, H (F, H)	DNA (5'-D(*GP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*GP*AP*GP*CP*GP*CP*CP*GP*A)-3')	polymer	21	6548.2	2		Homo sapiens
4	I, K, L (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	J, M (A, C)	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT)
6	N, O, P, Q, R... (A, B, C, D, E...)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 210 (UniProt: Q89268)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ser 151	Cys 151	engineered mutation
Phe 156	Tyr 156	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	123989.9
Non-Polymers*	Number of molecules	5
	Total formula weight	457.2
All*	Total formula weight	124447.0

*Water molecules are not included.