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5BXU

Human Tankyrase-2 in Complex with Macrocyclised Extended Peptide cp4n4m5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tankyrase-2polymer16417736.01UniProt (Q9H2K2)
Pfam (PF12796)
Homo sapiens (Human)TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein
2B
(B)
cp4n4m5polymer9829.81Homo sapiens
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)Homo sapiens
4D
(B)
4,4'-pentane-1,5-diylbis(1-propyl-1H-1,2,3-triazole)non-polymer290.41Chemie (4XQ)Homo sapiens
5E, F
(A, B)
waterwater18.0156Chemie (HOH)
Sequence modifications
A: 488 - 649 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Gly 486-expression tag
Ser 487-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight18565.8
Non-Polymers*Number of molecules2
Total formula weight325.9
All*Total formula weight18891.7
*Water molecules are not included.

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PDB entries from 2025-07-16

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