5BX6
PKA in complex with a halogenated phthalazinone fragment compound.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 351 | 40888.5 | 1 | UniProt (P17612) Pfam (PF00069) In PDB | Homo sapiens (Human) | PKA C-alpha |
| 2 | B | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (P61925) In PDB | Homo sapiens | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
| 3 | A | 4-chlorophthalazin-1(2H)-one | non-polymer | 180.6 | 1 | Chemie (495) | |||
| 4 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 5 | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43115.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 535.1 | |
| All* | Total formula weight | 43650.1 |
