5BWO
Crystal Structure of Human SIRT3 in Complex with a Palmitoyl H3K9 Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Palmitoyl H3K9 Peptide | polymer | 10 | 1093.2 | 1 | UniProt (by SIFTS) (Q6NXT2) | synthetic construct | |
| 2 | B (A) | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | polymer | 309 | 34402.4 | 1 | UniProt (Q9NTG7) Pfam (PF02146) | Homo sapiens (Human) | hSIRT3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3 |
| 3 | C (B) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F (B, A) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A: 118 - 399 (UniProt: Q9NTG7)
| PDB | External Database | Details |
|---|---|---|
| Met 91 | - | expression tag |
| Ala 92 | - | expression tag |
| Ser 93 | - | expression tag |
| Met 94 | - | expression tag |
| Thr 95 | - | expression tag |
| Gly 96 | - | expression tag |
| Gly 97 | - | expression tag |
| Gln 98 | - | expression tag |
| Gln 99 | - | expression tag |
| Met 100 | - | expression tag |
| Gly 101 | - | expression tag |
| Arg 102 | - | expression tag |
| Gly 103 | - | expression tag |
| Ser 104 | - | expression tag |
| His 105 | - | expression tag |
| His 106 | - | expression tag |
| His 107 | - | expression tag |
| His 108 | - | expression tag |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| Glu 111 | - | expression tag |
| Asn 112 | - | expression tag |
| Leu 113 | - | expression tag |
| Tyr 114 | - | expression tag |
| Phe 115 | - | expression tag |
| Gln 116 | - | expression tag |
| Gly 117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35495.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 321.8 | |
| All* | Total formula weight | 35817.5 |
