5BWM

The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transforming protein RhoA	polymer	179	20235.2	1	UniProt (P61586) Pfam (PF00071)	Homo sapiens (Human)	Rho cDNA clone 12,h12
2	B (B)	ADP-ribosyltransferase	polymer	219	25288.8	1	UniProt (Q8KNY0)	Bacillus cereus
3	C (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
4	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
5	E (B)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	1	Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (94865921) PubChem (94865923) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (124432988) PubChem (140875346) PubChem (11250888) PubChem (12309341) PubChem (124934831) PubChem (124934833) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875)
6	F, G (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
7	H, I (A, B)	water	water		18.0	55	Chemie (HOH)

Sequence modifications

A: 1 - 179 (UniProt: P61586)

PDB	External Database	Details
Asn 25	Phe 25	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45524.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1257.1
All*	Total formula weight	46781.0

*Water molecules are not included.