5BVJ
The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1beta
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | canakinumab Fab light-chain | polymer | 214 | 23381.9 | 4 | Homo sapiens (Human) | ILARIS Fab, canakinumab Fab | |
| 2 | B, D, F, H (B, D, F, H) | canakinumab Fab heavy-chain | polymer | 225 | 24179.1 | 4 | Homo sapiens (Human) | ILARIS Fab, canakinumab Fab | |
| 3 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 1234 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 190243.8 | |
| All* | Total formula weight | 190243.8 |
