5BO3

Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Anthranilate phosphoribosyltransferase	polymer	379	38948.0	2	UniProt (A5U4M0) Pfam (PF02885) Pfam (PF00591) In PDB	Mycobacterium tuberculosis
2	A, B	2-[(2-carboxyphenyl)amino]-5-(4-phosphonobutoxy)benzoic acid	non-polymer		409.3	2	Chemie (7P2)
3	A, B	IMIDAZOLE	non-polymer		69.1	2	Chemie (IMD)
4		water	water		18.0	402	Chemie (HOH)

Sequence modifications

A, B: 2 - 370 (UniProt: A5U4M0)

PDB	External Database	Details
Met 0	-	initiating methionine
Val 1	-	expression tag
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77896.0
Non-Polymers*	Number of molecules	4
	Total formula weight	956.8
All*	Total formula weight	78852.8

*Water molecules are not included.