5BNE

Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Anthranilate phosphoribosyltransferase	polymer	379	38948.0	4	UniProt (P9WFX5) Pfam (PF02885) Pfam (PF00591)	Mycobacterium tuberculosis
2	E, G, K (A, B, D)	2-[(2-carboxyphenyl)amino]-5-[(5-phosphonopentyl)oxy]benzoic acid	non-polymer		423.4	3	Chemie (7P3)
3	F, H, I, J (A, B, C)	IMIDAZOLE	non-polymer		69.1	4	Chemie (IMD)
4	L, M, N, O (A, B, C, D)	water	water		18.0	353	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 370 (UniProt: P9WFX5)

PDB	External Database	Details
Met 0	-	initiating methionine
Val 1	-	expression tag
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	155792.0
Non-Polymers*	Number of molecules	7
	Total formula weight	1546.4
All*	Total formula weight	157338.5

*Water molecules are not included.