5BMM
Src in complex with DNA-templated macrocyclic inhibitor MC25b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase Src | polymer | 286 | 32726.6 | 2 | UniProt (P00523) Pfam (PF07714) | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | C, D (C, D) | macrocyclic inhibitor MC25b | polymer | 5 | 740.8 | 2 | BIRD (PRD_002183) | synthetic construct | |
| 3 | E, F, G (A, B, C) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 251 - 533 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 248 | - | expression tag |
| His 249 | - | expression tag |
| Met 250 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66934.8 | |
| All* | Total formula weight | 66934.8 |
