5AYY

CRYSTAL STRUCTURE OF HUMAN QUINOLINATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH THE REACTANT QUINOLINATE

Replaces:  4R3X

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	polymer	305	31916.6	9	UniProt (V9HWJ5) Pfam (PF02749) Pfam (PF01729) UniProt (by SIFTS) (Q15274) In PDB	Homo sapiens (Human)	Quinolinate phosphoribosyltransferase [decarboxylating]
2	A, B, C, D, E...	QUINOLINIC ACID	non-polymer		167.1	9	Chemie (NTM)
3		water	water		18.0	37	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I: 1 - 297 (UniProt: V9HWJ5)

PDB	External Database	Details
Leu 298	-	expression tag
Glu 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	287249.8
Non-Polymers*	Number of molecules	9
	Total formula weight	1504.1
All*	Total formula weight	288753.9

*Water molecules are not included.