5AYT

Crystal structure of transthyretin in complex with L6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transthyretin	polymer	159	17310.5	2	UniProt (P02766) Pfam (PF00576)	Homo sapiens (Human)	ATTR,Prealbumin,TBPA
2	C, D (A, B)	2-oxidanyl-6-(phenylcarbonyl)benzo[de]isoquinoline-1,3-dione	non-polymer		317.3	2	Chemie (L6Y)
3	E, F (A, B)	water	water		18.0	244	Chemie (HOH)

Sequence modifications

A, B: -19 - 127 (UniProt: P02766)

PDB	External Database	Details
Met -31	-	expression tag
Arg -30	-	expression tag
Gly -29	-	expression tag
Ser -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34621.0
Non-Polymers*	Number of molecules	2
	Total formula weight	634.6
All*	Total formula weight	35255.6

*Water molecules are not included.