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5AXI

Crystal structure of Cbl-b TKB domain in complex with Cblin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
E3 ubiquitin-protein ligase CBL-Bpolymer30735908.23UniProt (Q3TTA7)
Pfam (PF02262)
Pfam (PF02761)
Pfam (PF02762)
Mus musculus (Mouse)Casitas B-lineage lymphoma proto-oncogene b,SH3-binding protein CBL-B,Signal transduction protein CBL-B
2D
(E)
Cblinpolymer5661.61UniProt (by SIFTS) (P35569)Mus musculus
3E, I, K
(A, B, C)
CALCIUM IONnon-polymer40.13Chemie (CA)
4F, G, H, J
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
5L, M, N, O
(A, B, C, E)
waterwater18.0167Chemie (HOH)
Sequence modifications
A, B, C: 38 - 343 (UniProt: Q3TTA7)
PDBExternal DatabaseDetails
Ser 37-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight108386.2
Non-Polymers*Number of molecules7
Total formula weight262.0
All*Total formula weight108648.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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