5AQC

KstR, transcriptional repressor of cholesterol degradation in Mycobacterium tuberculosis, bound to the cholesterol coenzyme A derivative, (25R)-3-oxocholest-4-en-26-oyl-CoA.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	HTH-TYPE TRANSCRIPTIONAL REPRESSOR KSTR	polymer	205	22825.0	2	UniProt (P96856) Pfam (PF00440) Pfam (PF17925)	MYCOBACTERIUM TUBERCULOSIS	KSTR
2	C, F (A, B)	(25S)-3-oxocholest-4-en-26-oyl-CoA	non-polymer		1164.1	2	Chemie (5JB)
3	D, H (A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
4	E (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	G (B)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	I, J (A, B)	water	water		18.0	227	Chemie (HOH)

Sequence modifications

A, B: 23 - 220 (UniProt: P96856)

PDB	External Database	Details
Met 22	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45650.0
Non-Polymers*	Number of molecules	6
	Total formula weight	2752.8
All*	Total formula weight	48402.8

*Water molecules are not included.