5AOE

Crystal structure of pneumolysin D168A mutant.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PNEUMOLYSIN	polymer	488	54794.2	2	UniProt (Q04IN8) Pfam (PF01289) Pfam (PF17440) UniProt (by SIFTS) (Q7ZAK5)	STREPTOCOCCUS PNEUMONIAE	THIOL-ACTIVATED CYTOLYSIN, CHOLESTEROL DEPENDENT CYTOLYSIN
2	C, D (A, B)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

A, B: 1 - 471 (UniProt: Q04IN8)

PDB	External Database	Details
Ala -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Glu 151	Asp 168	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	109588.3
All*	Total formula weight	109588.3

*Water molecules are not included.