5AHM

IMP-bound form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE	polymer	400	41702.6	2	UniProt (Q9HXM5) Pfam (PF00478)	PSEUDOMONAS AERUGINOSA PAO1	IMP DEHYDROGENASE, IMPD, IMPDH
2	C, F (A, B)	INOSINIC ACID	non-polymer		348.2	2	Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734)
3	D, E, G, H, I (A, B)	PHOSPHATE ION	non-polymer		95.0	5	Chemie (PO4) PubChem (1061)
4	J, K (A, B)	water	water		18.0	571	Chemie (HOH)

Sequence modifications

A, B: 1 - 92 (UniProt: Q9HXM5)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83405.1
Non-Polymers*	Number of molecules	7
	Total formula weight	1171.3
All*	Total formula weight	84576.4

*Water molecules are not included.