5AGY

CRYSTAL STRUCTURE OF A TAU CLASS GST MUTANT FROM GLYCINE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	GLUTATHIONE S-TRANSFERASE	polymer	219	25555.6	2	UniProt (O49235) Pfam (PF02798) Pfam (PF13410) UniProt (by SIFTS) (I1MJ34) In PDB	GLYCINE MAX (SOYBEAN)	GMGSTU4-MUTANT
2	A, B	4-NITROPHENYL METHANETHIOL	non-polymer		170.2	3	Chemie (4NM)
3	A, B	S-(P-NITROBENZYL)GLUTATHIONE	non-polymer		442.4	2	Chemie (GTB)
4	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
5		water	water		18.0	410	Chemie (HOH)

Sequence modifications

A, B: 3 - 219 (UniProt: O49235)

PDB	External Database	Details
Met 1	-	expression tag
Gln 2	-	expression tag
Gln 38	Arg 38	engineered mutation
Lys 46	Gln 46	engineered mutation
Cys 114	Trp 114	engineered mutation
Val 183	Ile 183	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51111.2
Non-Polymers*	Number of molecules	7
	Total formula weight	1585.5
All*	Total formula weight	52696.6

*Water molecules are not included.