5AGW

Bcl-2 alpha beta-1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1, APOPTOSIS REGULATOR BCL-2	polymer	166	19357.6	2	UniProt (P10415) UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB	HOMO SAPIENS (HUMAN)	BCL2-L-1, APOPTOSIS REGULATOR BCL-X
2	C, D	BCL-2-LIKE PROTEIN 11	polymer	22	2711.2	2	UniProt (O43521) Pfam (PF08945) In PDB	HOMO SAPIENS (HUMAN)	BCL2-L-11, BCL2-INTERACTING MEDIATOR OF CELL DEATH
3		water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B: 1 - 34 (UniProt: P10415)
A, B: 92 - 207 (UniProt: P10415)
A, B: 76 - 91 (UniProt: Q07817)
C, D: 1 - 21 (UniProt: O43521)

PDB	External Database	Details
Ace -1	-	acetylation
Xcp 2	Trp 147	engineered mutation
Aje 6	Glu 151	engineered mutation
Mh8 9	Arg 154	engineered mutation
Mh8 13	Glu 158	engineered mutation
Xcp 16	Ala 161	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	44137.5
All*	Total formula weight	44137.5

*Water molecules are not included.