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5AFJ

alpha7-AChBP in complex with lobeline and fragment 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
ACETYLCHOLINE-BINDING PROTEIN, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7polymer20523697.85Pfam (PF02931)
UniProt (by SIFTS) (P36544)
UniProt (by SIFTS) (P58154)
HOMO SAPIENS (HUMAN)ALPHA7-ACHBP, ACH-BINDING PROTEIN, ACHBP
2DA, EA, F, G, K...
(E, A, B, C, D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
3AA, FA, GA, H, I...
(D, E, A, B, C)
(3S)-6-(4-bromophenyl)-3-hydroxy-1,3-dimethyl-2,3-dihydropyridin-4(1H)-onenon-polymer296.210Chemie (42R)
4BA, HA, J, O, T
(D, E, A, B, C)
Alpha-Lobelinenon-polymer337.55Chemie (L0B)
5CA, IA, U
(D, E, C)
GLYCEROLnon-polymer92.13Chemie (GOL)
6X
(D)
beta-D-mannopyranosenon-polymer180.21Chemie (BMA)
7Y
(D)
alpha-D-mannopyranosenon-polymer180.21Chemie (MAN)
8JA, KA, LA, MA, NA
(A, B, C, D, E)
waterwater18.0663Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight118489.2
Non-Polymers*Number of molecules30
Total formula weight7497.5
All*Total formula weight125986.7
*Water molecules are not included.

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PDB entries from 2025-12-17

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