5ABU

Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	polymer	184	21249.0	1	UniProt (P48598) Pfam (PF01652)	DROSOPHILA MELANOGASTER (FRUIT FLY)	EIF-4E, EIF4E, EIF-4F 25 KDA SUBUNIT, MRNA CAP-BINDING PROT PROTEIN
2	B (B)	4E-BINDING PROTEIN MEXTLI	polymer	70	8225.2	1	UniProt (Q9VR35)	DROSOPHILA MELANOGASTER (FRUIT FLY)
3	C (A)	7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE	non-polymer		803.4	1	Chemie (GTG)
4	D (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	E, F (A, B)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 69 - 248 (UniProt: P48598)

PDB	External Database	Details
Gly 65	-	expression tag
Pro 66	-	expression tag
His 67	-	expression tag
Met 68	-	expression tag

B: 577 - 640 (UniProt: Q9VR35)

PDB	External Database	Details
Gly 571	-	expression tag
Pro 572	-	expression tag
His 573	-	expression tag
Met 574	-	expression tag
Leu 575	-	expression tag
Glu 576	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29474.3
Non-Polymers*	Number of molecules	2
	Total formula weight	838.9
All*	Total formula weight	30313.2

*Water molecules are not included.