Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003723 | molecular_function | RNA binding |
A | 0003743 | molecular_function | translation initiation factor activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006413 | biological_process | translational initiation |
B | 0008190 | molecular_function | eukaryotic initiation factor 4E binding |
B | 0045727 | biological_process | positive regulation of translation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE GTG A 1249 |
Chain | Residue |
A | TRP89 |
A | HOH2057 |
A | HOH2058 |
B | GLU584 |
B | HIS585 |
B | TYR588 |
B | HOH2006 |
A | MET92 |
A | GLY121 |
A | MET134 |
A | TRP135 |
A | GLU136 |
A | ARG188 |
A | LYS193 |
A | HOH2041 |
site_id | AC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL B 1636 |
Functional Information from PROSITE/UniProt
site_id | PS00813 |
Number of Residues | 24 |
Details | IF4E Eukaryotic initiation factor 4E signature. DYslFKknIrPmWEDaankqGGRW |
Chain | Residue | Details |
A | ASP123-TRP146 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP100 | |
A | TRP146 | |
A | ALA199 | |