5A8H
cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (A, G, M) | HIV-1 GP120 | polymer | 313 | 34838.7 | 3 | Pfam (PF00516) UniProt (by SIFTS) (P35961) | HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1) | |
| 2 | B, H, N (B, H, N) | T-CELL SURFACE GLYCOPROTEIN CD4 | polymer | 185 | 20503.3 | 3 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) | HOMO SAPIENS (HUMAN) | T-CELL SURFACE ANTIGEN T4/LEU-3, CD4 |
| 3 | C, I, O (C, I, O) | FAB OF BROADLY NEUTRALIZING ANTIBODY 17B | polymer | 214 | 23399.9 | 3 | HOMO SAPIENS (HUMAN) | ||
| 4 | D, J, P (D, J, P) | FAB OF BROADLY NEUTRALIZING ANTIBODY 17B | polymer | 229 | 24457.4 | 3 | HOMO SAPIENS (HUMAN) | ||
| 5 | E, K, Q (E, K, Q) | FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195 VARIANT G52K5 | polymer | 215 | 23402.0 | 3 | HOMO SAPIENS (HUMAN) | ||
| 6 | F, L, R (F, L, R) | FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195 VARIANT G52K5 | polymer | 244 | 26125.3 | 3 | HOMO SAPIENS (HUMAN) | ||
| 7 | AA, AB, BA, BB, CA... (A, M, F, G, R...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 45 | Chemie (NAG) |
Sequence modifications
B, H, N: 1 - 183 (UniProt: P01730)
| PDB | External Database | Details |
|---|---|---|
| Asn 184 | - | expression tag |
| Thr 185 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 458179.5 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 9954.4 | |
| All* | Total formula weight | 468133.8 |
