5A7J
Crystal structure of INPP5B in complex with benzene 1,2,4,5- tetrakisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE | polymer | 313 | 36201.1 | 2 | UniProt (P32019) Pfam (PF22669) | HOMO SAPIENS (HUMAN) | 75 KDA INOSITOL POLYPHOSPHATE-5-PHOSPHATASE, PHOSPHOINOSITIDE 5-PHOSPHATASE, 5PTASE, TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE, ISOFORM 2 |
| 2 | C, F, G, I (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | D, H (A, B) | (2,4,5-triphosphonooxyphenyl) dihydrogen phosphate | non-polymer | 462.0 | 2 | Chemie (K2Y) | |||
| 4 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B: 259 - 563 (UniProt: P32019)
| PDB | External Database | Details |
|---|---|---|
| Met 258 | - | expression tag |
| Ala 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
| His 567 | - | expression tag |
| His 568 | - | expression tag |
| His 569 | - | expression tag |
| His 570 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72402.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1400.4 | |
| All* | Total formula weight | 73802.6 |
