5A7J

Crystal structure of INPP5B in complex with benzene 1,2,4,5- tetrakisphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE	polymer	313	36201.1	2	UniProt (P32019) In PDB	HOMO SAPIENS (HUMAN)	75 KDA INOSITOL POLYPHOSPHATE-5-PHOSPHATASE, PHOSPHOINOSITIDE 5-PHOSPHATASE, 5PTASE, TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE, ISOFORM 2
2	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	A, B	(2,4,5-triphosphonooxyphenyl) dihydrogen phosphate	non-polymer		462.0	2	Chemie (K2Y)
4	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	76	Chemie (HOH)

Sequence modifications

A, B: 259 - 563 (UniProt: P32019)

PDB	External Database	Details
Met 258	-	expression tag
Ala 564	-	expression tag
His 565	-	expression tag
His 566	-	expression tag
His 567	-	expression tag
His 568	-	expression tag
His 569	-	expression tag
His 570	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72402.2
Non-Polymers*	Number of molecules	7
	Total formula weight	1400.4
All*	Total formula weight	73802.6

*Water molecules are not included.