5A7I

Crystal structure of INPP5B in complex with biphenyl 3,3',4,4',5,5'- hexakisphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE	polymer	313	36201.1	1	UniProt (P32019) In PDB	HOMO SAPIENS (HUMAN)	75 KDA INOSITOL POLYPHOSPHATE-5-PHOSPHATASE, PHOSPHOINOSITIDE 5-PHOSPHATASE, 5PTASE, TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE, ISOFORM 2
2	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	A	Biphenyl 3,3',4,4',5,5'-hexakisphosphate	non-polymer		730.1	1	Chemie (B6K)
4	A	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
5	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7		water	water		18.0	28	Chemie (HOH)

Sequence modifications

A: 259 - 563 (UniProt: P32019)

PDB	External Database	Details
Met 258	-	expression tag
Ala 564	-	expression tag
His 565	-	expression tag
His 566	-	expression tag
His 567	-	expression tag
His 568	-	expression tag
His 569	-	expression tag
His 570	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36201.1
Non-Polymers*	Number of molecules	7
	Total formula weight	1166.8
All*	Total formula weight	37367.9

*Water molecules are not included.