5A7I
Crystal structure of INPP5B in complex with biphenyl 3,3',4,4',5,5'- hexakisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE | polymer | 313 | 36201.1 | 1 | UniProt (P32019) Pfam (PF22669) | HOMO SAPIENS (HUMAN) | 75 KDA INOSITOL POLYPHOSPHATE-5-PHOSPHATASE, PHOSPHOINOSITIDE 5-PHOSPHATASE, 5PTASE, TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE, ISOFORM 2 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | Biphenyl 3,3',4,4',5,5'-hexakisphosphate | non-polymer | 730.1 | 1 | Chemie (B6K) | |||
| 4 | D, F, G (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | I (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 259 - 563 (UniProt: P32019)
| PDB | External Database | Details |
|---|---|---|
| Met 258 | - | expression tag |
| Ala 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
| His 567 | - | expression tag |
| His 568 | - | expression tag |
| His 569 | - | expression tag |
| His 570 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36201.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1166.8 | |
| All* | Total formula weight | 37367.9 |
