5A7C
Crystal structure of the second bromodomain of human BRD3 in complex with compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | BROMODOMAIN-CONTAINING PROTEIN 3 | polymer | 113 | 13307.4 | 4 | UniProt (Q15059) Pfam (PF00439) | HOMO SAPIENS (HUMAN) | RING3-LIKE PROTEIN |
| 2 | E, H, J, L (A, B, C, D) | N-(6-ACETAMIDOHEXYL)ACETAMIDE | non-polymer | 200.3 | 4 | Chemie (5D4) | |||
| 3 | F, G, I, K, M (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 306 - 416 (UniProt: Q15059)
| PDB | External Database | Details |
|---|---|---|
| Ser 304 | - | expression tag |
| Met 305 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53229.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1111.5 | |
| All* | Total formula weight | 54341.0 |
