5A5W
Crystal structure of Salmonella enterica HisA D7N D176A with ProFAR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase | polymer | 253 | 27086.9 | 1 | UniProt (A0A630AQ07) Pfam (PF00977) UniProt (by SIFTS) (P10372) | Salmonella enterica | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase |
| 2 | B (A) | [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | non-polymer | 577.3 | 1 | Chemie (GUO) | |||
| 3 | C (A) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 1 - 245 (UniProt: A0A630AQ07)
| PDB | External Database | Details |
|---|---|---|
| Asn 7 | Asp 7 | engineered mutation |
| Ala 176 | Asp 176 | engineered mutation |
| Lys 246 | - | expression tag |
| Gly 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27086.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 577.3 | |
| All* | Total formula weight | 27664.3 |
