5A5Q
Crystal structure of human ATAD2 bromodomain in complex with 3-methyl- 8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one hydrochloride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 | polymer | 130 | 15453.5 | 1 | UniProt (Q6PL18) Pfam (PF00439) | HOMO SAPIENS (HUMAN) | AAA NUCLEAR COREGULATOR CANCER-ASSOCIATED PROTEIN, ANCCA, H UMAN ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 |
| 2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D (A) | 3-methyl-8-[(piperidin-4-yl)amino]-1,2-dihydro-1,7-naphthyridin-2-one | non-polymer | 258.3 | 1 | Chemie (6XC) | |||
| 4 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
A: 981 - 1108 (UniProt: Q6PL18)
| PDB | External Database | Details |
|---|---|---|
| Ser 979 | - | expression tag |
| Met 980 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15453.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 574.6 | |
| All* | Total formula weight | 16028.1 |
