5A3S
Crystal structure of the (SR) Calcium ATPase E2-vanadate complex bound to thapsigargin and TNP-ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SARCOPLASMIC RETICULUM CALCIUM ATPASE 1 MOLECULE SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 | polymer | 995 | 109628.6 | 2 | UniProt (P04191) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) | ORYCTOLAGUS CUNICULUS (RABBIT) | SERCA1, SR CA(2+)-ATPASE 1, CALCIUM PUMP 1, CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC RETICULUM TYPE, FAST TWITCH ENDOPLASMIC RETICULUM CLASS 1/2 CA(2+) ATPASE, SARCOPLASMIC RETICULUM |
| 2 | C, J (A, B) | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER | non-polymer | 650.8 | 2 | Chemie (TG1) | |||
| 3 | D, K (A, B) | oxido(dioxo)vanadium | non-polymer | 98.9 | 2 | Chemie (VN4) | |||
| 4 | E, L (A, B) | SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE | non-polymer | 718.3 | 2 | Chemie (128) | |||
| 5 | F, G, M, N (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | H, O (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 7 | I, P (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 994 (UniProt: P04191)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 219257.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3182.2 | |
| All* | Total formula weight | 222439.5 |
