4ZZN
Human ERK2 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MITOGEN-ACTIVATED PROTEIN KINASE 1 | polymer | 350 | 40792.0 | 1 | UniProt (P28482) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | MAP KINASE 1, MAPK 1, ERT1, EXTRACELLULAR SIGNAL-REGULATED KINASE 2, ERK-2, MAP KINASE ISOFORM P42, P42-MAPK, MITOGEN-ACTIVATED PROTEIN KINASE 2, MAP KINASE 2, MAPK 2 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-N-methyl-benzamide | non-polymer | 360.8 | 1 | Chemie (CQ8) | |||
| 4 | D (A) | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A: 9 - 358 (UniProt: P28482)
| PDB | External Database | Details |
|---|---|---|
| Leu 44 | Val 46 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40792.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 456.9 | |
| All* | Total formula weight | 41248.9 |
