4ZZH
SIRT1/Activator Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | NAD-dependent protein deacetylase sirtuin-1 | polymer | 356 | 40125.3 | 1 | UniProt (Q96EB6) Pfam (PF02146) In PDB | Homo sapiens (Human) | hSIRT1,Regulatory protein SIR2 homolog 1,SIR2-like protein 1,hSIR2 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | (4S)-N-[3-(1,3-oxazol-5-yl)phenyl]-7-[3-(trifluoromethyl)phenyl]-3,4-dihydro-1,4-methanopyrido[2,3-b][1,4]diazepine-5(2H)-carboxamide | non-polymer | 491.5 | 1 | Chemie (4TO) |
Sequence modifications
A: 183 - 632 (UniProt: Q96EB6)
PDB | External Database | Details |
---|---|---|
Gly 633 | - | expression tag |
Gly 634 | - | expression tag |
Gly 635 | - | expression tag |
Ser 636 | - | expression tag |
Gly 637 | - | expression tag |
Gly 638 | - | expression tag |
Gly 639 | - | expression tag |
Ser 640 | - | expression tag |
Gln 641 | - | expression tag |
Tyr 642 | - | expression tag |
Leu 643 | - | expression tag |
Phe 644 | - | expression tag |
Leu 645 | - | expression tag |
Pro 646 | - | expression tag |
Pro 647 | - | expression tag |
Asn 648 | - | expression tag |
Arg 649 | - | expression tag |
Tyr 650 | - | expression tag |
Ile 651 | - | expression tag |
Phe 652 | - | expression tag |
His 653 | - | expression tag |
Gly 654 | - | expression tag |
Ala 655 | - | expression tag |
Glu 656 | - | expression tag |
Val 657 | - | expression tag |
Tyr 658 | - | expression tag |
Ser 659 | - | expression tag |
Asp 660 | - | expression tag |
Ser 661 | - | expression tag |
Glu 662 | - | expression tag |
Asp 663 | - | expression tag |
Asp 664 | - | expression tag |
Val 665 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40125.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 556.9 | |
All* | Total formula weight | 40682.1 |