4ZWJ
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin | polymer | 906 | 100861.1 | 4 | UniProt (P00720) UniProt (P08100) UniProt (P20443) Pfam (PF00959) Pfam (PF10413) Pfam (PF00001) Pfam (PF00339) Pfam (PF02752) | Enterobacteria phage T4 | Lysis protein,Lysozyme,Muramidase,Opsin-2,48 kDa protein,Retinal S-antigen,S-AG,Rod photoreceptor arrestin |
Sequence modifications
A, B, C, D: 1002 - 1161 (UniProt: P00720)
A, B, C, D: 1 - 348 (UniProt: P08100)
A, B, C, D: 2010 - 2392 (UniProt: P20443)
| PDB | External Database | Details |
|---|---|---|
| Gly 1012 | Arg 12 | engineered mutation |
| Thr 1054 | Cys 54 | engineered mutation |
| Ala 1097 | Cys 97 | engineered mutation |
| Arg 1137 | Ile 137 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Cys 2 | Asn 2 | engineered mutation |
| Gln 113 | Glu 113 | engineered mutation |
| Tyr 257 | Met 257 | engineered mutation |
| Cys 282 | Asn 282 | engineered mutation |
| Ala 1995 | - | linker |
| Ala 1996 | - | linker |
| Ala 1997 | - | linker |
| Gly 1998 | - | linker |
| Ser 1999 | - | linker |
| Ala 2000 | - | linker |
| Gly 2001 | - | linker |
| Ser 2002 | - | linker |
| Ala 2003 | - | linker |
| Gly 2004 | - | linker |
| Ser 2005 | - | linker |
| Ala 2006 | - | linker |
| Gly 2007 | - | linker |
| Ser 2008 | - | linker |
| Ala 2009 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 2374 | Leu 374 | engineered mutation |
| Ala 2375 | Val 375 | engineered mutation |
| Ala 2376 | Phe 376 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 403444.4 | |
| All* | Total formula weight | 403444.4 |
